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STMicroelectronics (NYSE: STM) revealed its highly integrated mobile-security solution, the ST54J, a system-on-chip (SoC) containing an NFC (Near-Field Communication) controller, Secure Element, and eSIM. The SoC delivers performance-boosting integration for mobile and IoT devices, with the added benefit of ST’s software-partner ecosystem for smoother user experiences in mobile payments and e-ticketing transactions, as well as more convenient, remote, mobile provisioning to support multiple operator subscriptions.

“As mobile devices require more security and connectivity in an ever-shrinking PCB footprint, the ST54J will help designers simplify assembly and reduce bill-of-material costs,” said Laurent Degauque, Marketing Director, Secure Microcontroller Division, STMicroelectronics. “ST’s established ecosystem of third-party software partners provides access to eSIM and eSE solutions that are not only EMVCo and GSMA-SAS certifiable, but also tested for interoperability and validated with numerous Mobile Network Operators (MNOs), custom profiles and application providers worldwide.”

Spearheading the fourth generation of ST’s proven embedded Secure Element family, the single-chip ST54J ensures faster contactless interaction than a discrete chipset by eliminating performance-limiting off-chip data exchanges between the Secure Element and NFC controller. In addition, a faster, state-of-the-art core for each function further accelerates contactless transactions with mobile terminals and enhances roaming by supporting secure-element cryptographic protocols used worldwide, including FeliCa® and MIFARE®.

Packaging and design flexibility comes from the space savings of integrating three key functions onto a single chip. In addition, ST used its NFC booster technology to enhance the performance of the NFC controller, allowing it to establish robust contactless connections with a small-size antenna, allowing designers even more generous freedom to manage space inside the device and minimize the thickness of new smartphone generations.

ST delivers the ST54J to customers with NFC firmware and the GlobalPlatform V2.3 secure element Operating System, which provides best-in-class cryptographic performance and optimum eSIM interoperability. The OS also allows flexible configurations to support eSE-only or combined functionality. In addition, as the first chip maker accredited by the GSMA to personalize eSIMs for mobiles and connected IoT devices onto WLCSP packages, ST can shrink the supply chain and accelerate delivery to manufacturers.

Leti, a research institute of CEA Tech, today announced the launch of the REDFINCH consortium to develop the next generation of miniaturized, portable optical sensors for chemical detection in both gases and liquids. Initial target applications are in the petrochemical and dairy industries.

The consortium of eight European research institutes and companies will focus on developing novel, high-performance, cost-effective chemical sensors, based on mid-infrared photonic integrated circuits (MIR PICs). Silicon PICs — integrating optical circuits onto millimeter-size silicon chips — create extremely robust miniature systems, in which discrete components are replaced by on-chip equivalents. This makes them easier to use and reduces their cost dramatically, expected at least by a factor of 10.

To develop these chemical sensors, the consortium must overcome the significant challenge of implementing these capabilities in the important mid-infrared region (2-20 μm wavelength range), where many important chemical and biological species have strong absorption fingerprints. This allows both the detection and concentration measurement of a wide range of gases, liquids and biomolecules, which is crucial for applications such as health monitoring and diagnosis, detection of biological compounds and monitoring of toxic gases.

Initially, REDFINCH will focus on three specific applications:

  • Process gas analysis in refineries
  • Gas leak detection in petrochemical plants and pipelines
  • Protein analysis in liquids for the dairy industry.

Silicon photonics leverages the advantages of high-performance CMOS technology, providing low-cost mass manufacturing, high-fidelity reproduction of designs and access to high-refractive index contrasts that enable high-performance nanophotonics.

“Despite the mid-infrared wavelength region’s importance for a wide range of applications, current state-of-the-art sensing systems in the MIR tend to be large and delicate. This significantly limits their spreading in real-world applications,” said Jean-Guillaume Coutard, an instrumentation engineer at Leti, which is coordinating the project. “By harnessing the power of photonic integrated circuits, using hybrid and monolithic integration of III-V diode and interband cascade and quantum cascade materials with silicon, the consortium will create high-performance, cost-effective sensors for a number of industries.” 

In addition to Leti, whose expertise includes the design and manufacture of PICs on a 200mm pilot line and integrated photoacoustic cells on silicon, the consortium members and contributions include:

  • Cork Institute of Technology (Ireland) – PIC design & fabrication, hybrid integration
  • Université de Montpellier (France) – Laser growth on Si, photodetector growth
  • Technische Universität Wien (Austria) – Liquid spectroscopy, assembly/test of sensors
  • mirSense (France) – MIR sensor products, laser module integration
  • Argotech a.s. (Czech Republic) Assembly/packaging of PICs
  • Fraunhofer IPM (Germany) – Gas spectroscopy, instrument design/assembly
  • Endress+Hauser (Germany) Process gas analysis and expertise, testing validation.

A new wearable ultrasound patch that non-invasively monitors blood pressure in arteries deep beneath the skin could help people detect cardiovascular problems earlier on and with greater precision. In tests, the patch performed as well as some clinical methods to measure blood pressure.

Applications include real-time, continuous monitoring of blood pressure changes in patients with heart or lung disease, as well as patients who are critically ill or undergoing surgery. The patch uses ultrasound, so it could potentially be used to non-invasively track other vital signs and physiological signals from places deep inside the body.

A team of researchers led by the University of California San Diego describe their work in a paper published Sept. 11 in Nature Biomedical Engineering.

Wearable ultrasound patch tracks blood pressure in a deep artery or vein. Credit:
Chonghe Wang/Nature Biomedical Engineering

“Wearable devices have so far been limited to sensing signals either on the surface of the skin or right beneath it. But this is like seeing just the tip of the iceberg,” said Sheng Xu, a professor of nanoengineering at the UC San Diego Jacobs School of Engineering and the corresponding author of the study. “By integrating ultrasound technology into wearables, we can start to capture a whole lot of other signals, biological events and activities going on way below the surface in a non-invasive manner.”

“We are adding a third dimension to the sensing range of wearable electronics,” said Xu, who is also affiliated with the Center for Wearable Sensors at UC San Diego.

The new ultrasound patch can continuously monitor central blood pressure in major arteries as deep as four centimeters (more than one inch) below the skin.

Physicians involved with the study say the technology would be useful in various inpatient procedures.

“This has the potential to be a great addition to cardiovascular medicine,” said Dr. Brady Huang, a co-author on the paper and radiologist at UC San Diego Health. “In the operating room, especially in complex cardiopulmonary procedures, accurate real-time assessment of central blood pressure is needed–this is where this device has the potential to supplant traditional methods.”

A convenient alternative to clinical methods

The device measures central blood pressure–which differs from the blood pressure that’s measured with an inflatable cuff strapped around the upper arm, known as peripheral blood pressure. Central blood pressure is the pressure in the central blood vessels, which send blood directly from the heart to other major organs throughout the body. Medical experts consider central blood pressure more accurate than peripheral blood pressure and also say it’s better at predicting heart disease.

Measuring central blood pressure isn’t typically done in routine exams, however. The state-of-the-art clinical method is invasive, involving a catheter inserted into a blood vessel in a patient’s arm, groin or neck and guiding it to the heart.

A non-invasive method exists, but it can’t consistently produce accurate readings. It involves holding a pen-like probe, called a tonometer, on the skin directly above a major blood vessel. To get a good reading, the tonometer must be held steady, at just the right angle and with the right amount of pressure each time. But this can vary between tests and different technicians.

“It’s highly operator-dependent. Even with the proper technique, if you move the tonometer tip just a millimeter off, the data get distorted. And if you push the tonometer down too hard, it’ll put too much pressure on the vessel, which also affects the data,” said co-first author Chonghe Wang, a nanoengineering graduate student at UC San Diego. Tonometers also require the patient to sit still–which makes continuous monitoring difficult–and are not sensitive enough to get good readings through fatty tissue.

The UC San Diego-led team has developed a convenient alternative–a soft, stretchy ultrasound patch that can be worn on the skin and provide accurate, precise readings of central blood pressure each time, even while the user is moving. And it can still get a good reading through fatty tissue.

The patch was tested on a male subject, who wore it on the forearm, wrist, neck and foot. Tests were performed both while the subject was stationary and during exercise. Recordings collected with the patch were more consistent and precise than recordings from a commercial tonometer. The patch recordings were also comparable to those collected with a traditional ultrasound probe.

Making ultrasound wearable

“A major advance of this work is it transforms ultrasound technology into a wearable platform. This is important because now we can start to do continuous, non-invasive monitoring of major blood vessels deep underneath the skin, not just in shallow tissues,” said Wang.

The patch is a thin sheet of silicone elastomer patterned with what’s called an “island-bridge” structure–an array of small electronic parts (islands) that are each connected by spring-shaped wires (bridges). Each island contains electrodes and devices called piezoelectric transducers, which produce ultrasound waves when electricity passes through them. The bridges connecting them are made of thin, spring-like copper wires. The island-bridge structure allows the entire patch to conform to the skin and stretch, bend and twist without compromising electronic function.

The patch uses ultrasound waves to continuously record the diameter of a pulsing blood vessel located as deep as four centimeters below the skin. This information then gets translated into a waveform using customized software. Each peak, valley and notch in the waveform, as well as the overall shape of the waveform, represents a specific activity or event in the heart. These signals provide a lot of detailed information to doctors assessing a patient’s cardiovascular health. They can be used to predict heart failure, determine if blood supply is fine, etc.

Next steps

Researchers note that the patch still has a long way to go before it reaches the clinic. Improvements include integrating a power source, data processing units and wireless communication capability into the patch.

“Right now, these capabilities have to be delivered by wires from external devices. If we want to move this from benchtop to bedside, we need to put all these components on board,” said Xu.

The team is looking to collaborate with experts in data processing and wireless technologies for the next phase of the project.

By Michael Droeger

Are you ready for a shared economy where your transportation needs are no longer met by an automaker, but rather a “mobility service provider”? While smart transportation news has mostly focused on the likes of electrification (Tesla) and autonomy (Waymo), the real changes in transportation may be more fundamental than self-driving electric cars. According to presenters at this week’s Smart Automotive Summit at SEMICON Taiwan, new technologies won’t just make cars smarter: they will transform the way we see and use transportation in myriad ways.

Constance Chen, public relations general manager for forum sponsor Mercedes Benz, opened with a brief overview of parent Daimler’s evolving approach to transportation, dubbed CASE, which stands for Connected, Autonomous, Shared and Services, and Electric.

“The fundamental value of vehicles is changing,” Chen said, and car ownership is one of the biggest changes. Ride-sharing services like Uber and Lyft, and shared car services like ZipCar and DriveNow, are already addressing the transportation needs of a growing urban population that eschews car ownership. Traffic congestion, parking challenges, and a desire to improve air quality are key drivers (no pun intended) moving people away from car ownership to embrace shared transportation solutions.

Indeed, societal considerations are as challenging as some technological hurdles facing autonomous vehicle development. Robert Brown, Taiwan operations manager for Magma Electronics, listed his top five challenges for autonomous transportation:

  1. Perception (vision, sensors)
  2. Assessment (ability of systems to analyze data)
  3. Control (need for faster-than-human response)
  4. Communication (vehicle-to-vehicle, vehicle-to-everything)
  5. Expectations—specifically people’s expectations of the value autonomous transportation should deliver

As people change the way they view transportation and begin to understand what is possible when they can relinquish control of their vehicle, they’re transportation needs and expectations are likely to change. The challenges are, of course, also an opportunity to deliver a wide range of services, including information, entertainment, and retail, which opens the door for traditional carmakers to position themselves more as service providers like Mercedes Benz.

For those who have grown up with traditional car ownership and the perceived freedom that owning allows one to go anywhere at anytime, the idea of giving up their car—one that they drive themselves—might seem beyond the pale. But as ride-sharing services are already showing, a growing portion of our population seems more than ready to embrace a shared and autonomous future.

The SEMICON Taiwan Smart Automotive Summit is part of SEMI’s Smart Transportation initiative focusing on automotive electronics, a top priority for SEMI and its 2,000+ members. SEMI’s industry standards, technology communities, roadmap efforts, EH&S/regulatory activities and other global platforms and communities bring together the automotive and semiconductor supply chains to collaborate, increase cross-industry efficiencies and shorten the time to better business results.

Michael Droeger is director of marketing at SEMI. 

Originally published on the SEMI blog.

Leti, a research institute of CEA Tech, and VSORA, which specializes in multi-core digital signal processor (DSP) design, today announced they have demonstrated the implementation of 5G New Radio (5G NR) Release 15 on a new DSP architecture that can dramatically reduce time to market of digital modems.

Defined by the 3rd Generation Partnership Project (3GPP), 5G NR is the air interface, or wireless communication link, for the next generation of cellular networks. It is expected to significantly improve connectivity experiences in 5G cellular networks. 3GPP Release 15 of the 5G system architecture, finalized in June 2018, provides the set of features and functionality needed for deploying a commercially operational 5G system.

This first implementation of 5G NR Release 15 physical layer on VSORA’s multi-core DSP demonstrates that it can address timely and complex systems like 5G NR, while providing a highly flexible software-defined development flow. The demonstration has shown that VSORA’s development suite provided an optimized DSP architecture, able to support the concurrent reception of representative 5G quality-of-service regimes covering extreme broadband, narrowband Internet of Things and ultra-low latency systems.

“This new DSP development flow allows signal-processing engineers to evaluate different implementations of their algorithms for cost, processing power, arithmetic precision and power consumption, well before the physical implementation,” said VSORA CEO Khaled Maalej. “The same development flow lets algorithm engineers and software engineers share the same environment and source code, dramatically accelerating time-to-market for Release 15 architectures.”

“VSORA’s innovations simplify the design flow, which eliminates the need to develop HDL-based co-processors,” said Benoit Miscopein, head of Leti’s wireless broadband systems lab. “Our demonstration also shows their product can support a system as hungry in terms of computational resources as the 5G NR modem.”

“VSORA’s added value is the very high flexibility that the company offers in terms of testing various implementation architectural trade-offs,” Miscopein added. “This speeds time-to-market by reducing the time required to converge towards a suitable DSP architecture. The approach proposed by VSORA is also flexible in the sense that the DSP can fulfill the requirements of the standard evolution, e.g. Releases 16 and 17, without redesigning a complete architecture.”

“With the coming 5G mobile standard, traditional DSP technology will run out of steam on multiple levels,” added Maalej. “Our aim is to become the reference point for state-of-the-art DSP applications. VSORA’s technology has the potential to revolutionize DSP architectures, transform the design and implementation processes, and ultimately enhance go-to-market strategies.”

Myeloperoxidase – an enzyme naturally found in our lungs – can biodegrade pristine graphene, according to the latest discovery of Graphene Flagship partners in CNRS, University of Strasbourg (France), Karolinska Institute (Sweden) and University of Castilla-La Mancha (Spain). Among other projects, the Graphene Flagship designs flexible biomedical electronic devices that will interface with the human body. Such applications require graphene to be biodegradable, so it can be expelled from the body.

To test how graphene behaves within the body, researchers analysed how it was broken down with the addition of a common human enzyme – myeloperoxidase or MPO. If a foreign body or bacteria is detected, neutrophils surround it and secrete MPO, thereby destroying the threat. Previous work by Graphene Flagship partners found that MPO could successfully biodegrade graphene oxide.

However, the structure of non-functionalized graphene was thought to be more resistant to degradation. To test this, the team looked at the effects of MPO ex vivo on two graphene forms; single- and few-layer.

Alberto Bianco, researcher at Graphene Flagship Partner CNRS, explains: “We used two forms of graphene, single- and few-layer, prepared by two different methods in water. They were then taken and put in contact with myeloperoxidase in the presence of hydrogen peroxide. This peroxidase was able to degrade and oxidise them. This was really unexpected, because we thought that non-functionalized graphene was more resistant than graphene oxide.”

Rajendra Kurapati, first author on the study and researcher at Graphene Flagship Partner CNRS, remarks how “the results emphasize that highly dispersible graphene could be degraded in the body by the action of neutrophils. This would open the new avenue for developing graphene-based materials.”

With successful ex-vivo testing, in-vivo testing is the next stage. Bengt Fadeel, professor at Graphene Flagship Partner Karolinska Institute believes that “understanding whether graphene is biodegradable or not is important for biomedical and other applications of this material. The fact that cells of the immune system are capable of handling graphene is very promising.”

Prof. Maurizio Prato, the Graphene Flagship leader for its Health and Environment Work Package said that “the enzymatic degradation of graphene is a very important topic, because in principle, graphene dispersed in the atmosphere could produce some harm. Instead, if there are microorganisms able to degrade graphene and related materials, the persistence of these materials in our environment will be strongly decreased. These types of studies are needed.” “What is also needed is to investigate the nature of degradation products,” adds Prato. “Once graphene is digested by enzymes, it could produce harmful derivatives. We need to know the structure of these derivatives and study their impact on health and environment,” he concludes.

Prof. Andrea C. Ferrari, Science and Technology Officer of the Graphene Flagship, and chair of its management panel added: “The report of a successful avenue for graphene biodegradation is a very important step forward to ensure the safe use of this material in applications. The Graphene Flagship has put the investigation of the health and environment effects of graphene at the centre of its programme since the start. These results strengthen our innovation and technology roadmap.”

By stacking and connecting layers of stretchable circuits on top of one another, engineers have developed an approach to build soft, pliable “3D stretchable electronics” that can pack a lot of functions while staying thin and small in size. The work is published in the Aug. 13 issue of Nature Electronics.

This is the device compared to a US dollar coin. Credit: Zhenlong Huang

As a proof of concept, a team led by the University of California San Diego has built a stretchable electronic patch that can be worn on the skin like a bandage and used to wirelessly monitor a variety of physical and electrical signals, from respiration, to body motion, to temperature, to eye movement, to heart and brain activity. The device, which is as small and thick as a U.S. dollar coin, can also be used to wirelessly control a robotic arm.

“Our vision is to make 3D stretchable electronics that are as multifunctional and high-performing as today’s rigid electronics,” said senior author Sheng Xu, a professor in the Department of NanoEngineering and the Center for Wearable Sensors, both at the UC San Diego Jacobs School of Engineering.

Xu was named among MIT Technology Review’s 35 Innovators Under 35 list in 2018 for his work in this area.

To take stretchable electronics to the next level, Xu and his colleagues are building upwards rather than outwards. “Rigid electronics can offer a lot of functionality on a small footprint–they can easily be manufactured with as many as 50 layers of circuits that are all intricately connected, with a lot of chips and components packed densely inside. Our goal is to achieve that with stretchable electronics,” said Xu.

The new device developed in this study consists of four layers of interconnected stretchable, flexible circuit boards. Each layer is built on a silicone elastomer substrate patterned with what’s called an “island-bridge” design. Each “island” is a small, rigid electronic part (sensor, antenna, Bluetooth chip, amplifier, accelerometer, resistor, capacitor, inductor, etc.) that’s attached to the elastomer. The islands are connected by stretchy “bridges” made of thin, spring-shaped copper wires, allowing the circuits to stretch, bend and twist without compromising electronic function.

Making connections

This work overcomes a technological roadblock to building stretchable electronics in 3D. “The problem isn’t stacking the layers. It’s creating electrical connections between them so they can communicate with each other,” said Xu. These electrical connections, known as vertical interconnect accesses or VIAs, are essentially small conductive holes that go through different layers on a circuit. VIAs are traditionally made using lithography and etching. While these methods work fine on rigid electronic substrates, they don’t work on stretchable elastomers.

So Xu and his colleagues turned to lasers. They first mixed silicone elastomer with a black organic dye so that it could absorb energy from a laser beam. Then they fashioned circuits onto each layer of elastomer, stacked them, and then hit certain spots with a laser beam to create the VIAs. Afterward, the researchers filled in the VIAs with conductive materials to electrically connect the layers to one another. And a benefit of using lasers, notes Xu, is that they are widely used in industry, so the barrier to transfer this technology is low.

Multifunctional ‘smart bandage’

The team built a proof-of-concept 3D stretchable electronic device, which they’ve dubbed a “smart bandage.” A user can stick it on different parts of the body to wirelessly monitor different electrical signals. When worn on the chest or stomach, it records heart signals like an electrocardiogram (ECG). On the forehead, it records brain signals like a mini EEG sensor, and when placed on the side of the head, it records eyeball movements. When worn on the forearm, it records muscle activity and can also be used to remotely control a robotic arm. The smart bandage also monitors respiration, skin temperature and body motion.

“We didn’t have a specific end use for all these functions combined together, but the point is that we can integrate all these different sensing capabilities on the same small bandage,” said co-first author Zhenlong Huang, who conducted this work as a visiting Ph.D. student in Xu’s research group.

And the researchers did not sacrifice quality for quantity. “This device is like a ‘master of all trades.’ We picked high quality, robust subcomponents–the best strain sensor we could find on the market, the most sensitive accelerometer, the most reliable ECG sensor, high quality Bluetooth, etc.–and developed a clever way to integrate all these into one stretchable device,” added co-first author Yang Li, a nanoengineering graduate student at UC San Diego in Xu’s research group.

So far, the smart bandage can last for more than six months without any drop in performance, stretchability or flexibility. It can communicate wirelessly with a smartphone or laptop up to 10 meters away. The device runs on a total of about 35.6 milliwatts, which is equivalent to the power from 7 laser pointers.

The team will be working with industrial partners to optimize and refine this technology. They hope to test it in clinical settings in the future.

Implantation of a stent-like flow diverter can offer one option for less invasive treatment of brain aneurysms – bulges in blood vessels – but the procedure requires frequent monitoring while the vessels heal. Now, a multi-university research team has demonstrated proof-of-concept for a highly flexible and stretchable sensor that could be integrated with the flow diverter to monitor hemodynamics in a blood vessel without costly diagnostic procedures.

Woon-Hong Yeo, an assistant professor in Georgia Tech’s George W. Woodruff School of Mechanical Engineering and Wallace H. Coulter Department of Biomedical Engineering, holds a flow sensor on a stent backbone. (Credit: John Toon, Georgia Tech)

The sensor, which uses capacitance changes to measure blood flow, could reduce the need for testing to monitor the flow through the diverter. Researchers, led by Georgia Tech, have shown that the sensor accurately measures fluid flow in animal blood vessels in vitro, and are working on the next challenge: wireless operation that could allow in vivo testing.

The research was reported July 18 in the journal ACS Nano and was supported by multiple grants from Georgia Tech’s Institute for Electronics and Nanotechnology, the University of Pittsburgh and the Korea Institute of Materials Science.

“The nanostructured sensor system could provide advantages for patients, including a less invasive aneurysm treatment and an active monitoring capability,” said Woon-Hong Yeo, an assistant professor in Georgia Tech’s George W. Woodruff School of Mechanical Engineering and Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. “The integrated system could provide active monitoring of hemodynamics after surgery, allowing the doctor to follow up with quantitative measurement of how well the flow diverter is working in the treatment.”

Cerebral aneurysms occur in up to five percent of the population, with each aneurysm carrying a one percent risk per year of rupturing, noted Youngjae Chun, an associate professor in the Swanson School of Engineering at the University of Pittsburgh. Aneurysm rupture will cause death in up to half of affected patients.

Endovascular therapy using platinum coils to fill the aneurysm sac has become the standard of care for most aneurysms, but recently a new endovascular approach – a flow diverter – has been developed to treat cerebral aneurysms. Flow diversion involves placing a porous stent across the neck of an aneurysm to redirect flow away from the sac, generating local blood clots within the sac.

“We have developed a highly stretchable, hyper-elastic flow diverter using a highly-porous thin film nitinol,” Chun explained. “None of the existing flow diverters, however, provide quantitative, real-time monitoring of hemodynamics within the sac of cerebral aneurysm. Through the collaboration with Dr. Yeo’s group at Georgia Tech, we have developed a smart flow-diverter system that can actively monitor the flow alterations during and after surgery.”

Repairing the damaged artery takes months or even years, during which the flow diverter must be monitored using MRI and angiogram technology, which is costly and involves injection of a magnetic dye into the blood stream. Yeo and his colleagues hope their sensor could provide simpler monitoring in a doctor’s office using a wireless inductive coil to send electromagnetic energy through the sensor. By measuring how the energy’s resonant frequency changes as it passes through the sensor, the system could measure blood flow changes into the sac.

“We are trying to develop a batteryless, wireless device that is extremely stretchable and flexible that can be miniaturized enough to be routed through the tiny and complex blood vessels of the brain and then deployed without damage,” said Yeo. “It’s a very challenging to insert such electronic system into the brain’s narrow and contoured blood vessels.”

The sensor uses a micro-membrane made of two metal layers surrounding a dielectric material, and wraps around the flow diverter. The device is just a few hundred nanometers thick, and is produced using nanofabrication and material transfer printing techniques, encapsulated in a soft elastomeric material.

“The membrane is deflected by the flow through the diverter, and depending on the strength of the flow, the velocity difference, the amount of deflection changes,” Yeo explained. “We measure the amount of deflection based on the capacitance change, because the capacitance is inversely proportional to the distance between two metal layers.”

Because the brain’s blood vessels are so small, the flow diverters can be no more than five to ten millimeters long and a few millimeters in diameter. That rules out the use of conventional sensors with rigid and bulky electronic circuits.

“Putting functional materials and circuits into something that size is pretty much impossible right now,” Yeo said. “What we are doing is very challenging based on conventional materials and design strategies.”

The researchers tested three materials for their sensors: gold, magnesium and the nickel-titanium alloy known as nitinol. All can be safely used in the body, but magnesium offers the potential to be dissolved into the bloodstream after it is no longer needed.

The proof-of-principle sensor was connected to a guide wire in the in vitro testing, but Yeo and his colleagues are now working on a wireless version that could be implanted in a living animal model. While implantable sensors are being used clinically to monitor abdominal blood vessels, application in the brain creates significant challenges.

“The sensor has to be completely compressed for placement, so it must be capable of stretching 300 or 400 percent,” said Yeo. “The sensor structure has to be able to endure that kind of handling while being conformable and bending to fit inside the blood vessel.”

The research included multiple contributors from different institutions, including Connor Howe from Virginia Commonwealth University; Saswat Mishra and Yun-Soung Kim from Georgia Tech, Youngjae Chun, Yanfei Chen, Sang-Ho Ye and William Wagner from the University of Pittsburgh; Jae-Woong Jeong from the Korea Advanced Institute of Science and Technology; Hun-Soo Byun from Chonnam National University; and Jong-Hoon Kim from Washington State University.

Wearable devices are increasingly bought to track and measure health and sports performance: from the number of steps walked each day to a person’s metabolic efficiency, from the quality of brain function to the quantity of oxygen inhaled while asleep. But the truth is we know very little about how well these sensors and machines work — let alone whether they deliver useful information, according to a new review published in Frontiers in Physiology.

“Despite the fact that we live in an era of ‘big data,’ we know surprisingly little about the suitability or effectiveness of these devices,” says lead author Dr Jonathan Peake of the School of Biomedical Sciences and Institute of Health and Biomedical Innovation at the Queensland University of Technology in Australia. “Only five percent of these devices have been formally validated.”

The authors reviewed information on devices used both by everyday people desiring to keep track of their physical and psychological health and by athletes training to achieve certain performance levels. The devices — ranging from so-called wrist trackers to smart garments and body sensors designed to track our body’s vital signs and responses to stress and environmental influences — fall into six categories:

  • devices for monitoring hydration status and metabolism
  • devices, garments and mobile applications for monitoring physical and psychological stress
  • wearable devices that provide physical biofeedback (e.g., muscle stimulation, haptic feedback)
  • devices that provide cognitive feedback and training
  • devices and applications for monitoring and promoting sleep
  • devices and applications for evaluating concussion

The authors investigated key issues, such as: what the technology claims to do; whether the technology has been independently validated against some recognized standards; whether the technology is reliable and what, if any, calibration is needed; and finally, whether the item is commercially available or still under development.

The authors say that technology developed for research purposes generally seems to be more credible than devices created purely for commercial reasons.

“What is critical to understand here is that while most of these technologies are not labeled as ‘medical devices’ per se, their very existence, let alone the accompanying marketing, conveys a sensibility that they can be used to measure a standard of health,” says Peake. “There are ethical issues with this assumption that need to be addressed.”

For example, self-diagnosis based on self-gathered data could be inconsistent with clinical analysis based on a medical professional’s assessment. And just as body mass index charts of the past really only provided general guidelines and didn’t take into account a person’s genetic predisposition or athletic build, today’s technology is similarly limited.

The authors are particularly concerned about those technologies that seek to confirm or correlate whether someone has sustained or recovered from a concussion, whether from sports or military service.

“We have to be very careful here because there is so much variability,” says Peake. “The technology could be quite useful, but it can’t and should never replace assessment by a trained medical professional.”

Speaking generally again now, Peake says it is important to establish whether using wearable devices affects people’s knowledge and attitude about their own health and whether paying such close attention to our bodies could in fact create a harmful obsession with personal health, either for individuals using the devices, or for family members. Still, self-monitoring may reveal undiagnosed health problems, said Peake, although population data is more likely to point to false positives.

“What we do know is that we need to start studying these devices and the trends they are creating,” says Peake. “This is a booming industry.”

In fact, a March 2018 study by P&S Market Research indicates the wearable market is expected to generate $48.2 billion in revenue by 2023. That’s a mere five years into the future.”

The authors highlight a number of areas for investigation in order to develop reasonable consumer policies around this growing industry. These include how rigorously the device/technology has been evaluated and the strength of evidence that the device/technology actually produces the desired outcomes.

“And I’ll add a final question: Is wearing a device that continuously tracks your body’s actions, your brain activity, and your metabolic function — then wirelessly transmits that data to either a cloud-based databank or some other storage — safe, for users? Will it help us improve our health?” asked Peake. “We need to ask these questions and research the answers.”

Keysight Technologies, Inc. (NYSE: KEYS), a technology company that helps enterprises, service providers, and governments accelerate innovation to connect and secure the world, announced the Keysight MX0100A InfiniiMax micro probe head, the industry’s smallest solder-in probe head for high performance oscilloscopes, optimized for modern high-speed devices.

The size of electronic devices continues to shrink, resulting in smaller pads and narrower pitch spacing. Additionally, as data rates for applications such as DDR memory increase, conventional probing pads work as a stub, becoming a source for electromagnetic interference (EMI). As a result, customers are actively seeking high density, small geometry solutions for probing modern electronic technologies to analyze and measure signals without interference.

Keysight’s new InfiniiMax micro probe head is a micro solder-in head for use with the company’s InfiniiMax I/II probe amplifiers and is designed to access small geometry target devices. The lead wires can be adjusted to accommodate targets from 0 mm to 7 mm apart. When used in conjunction with Keysight’s 1169B 12 GHz InfiniiMax II probe amplifier, the MX0100A delivers up to full 12 GHz bandwidth. Offering the best probe loading performance in its class (0.17 pF, 50 kΩ differentially), the extremely low input capacitance of the MX0100A minimizes the probe loading effect and maximizes signal integrity when measuring high-speed signals.

“Existing oscilloscope probe head solutions available today are even larger than the devices being tested in some cases. This makes signal probing access a continual challenge for modern electronic technologies,” said Dave Cipriani, Vice President of the Digital and Photonics Center of Excellence at Keysight Technologies. “Unlike conventional solder-in probe heads in this class, Keysight specifically designed this micro probe to be less than half the size of existing solder-in probe heads for high density, fine pitch devices. It is the first, and only, of its kind on the market today.”